Effects of a botulinum toxin type A injection on the masseter muscle: An animal model study
¹Ú½Ã¿ª, ¹Ú¿µ¿í, Áö¿µÁØ, ¹Ú½Â¿í, ±è¼º°ï,
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¹Ú½Ã¿ª ( Park Si-Yeok ) - Gangneung-Wonju National University College of Dentistry Department of Oral and Maxillofacial Surgery
¹Ú¿µ¿í ( Park Young-Wook ) - Gangneung-Wonju National University College of Dentistry Department of Oral and Maxillofacial Surgery
Áö¿µÁØ ( Ji Young-Jun ) - Ulsan University Department of Biomedical Engineering
¹Ú½Â¿í ( Park Sung-Wook ) - Gangneung-Wonju National University Department of Electronic Engineering
±è¼º°ï ( Kim Seong-Gon ) - Gangneung-Wonju National University College of Dentistry Department of Oral and Maxillofacial Surgery
Abstract
Background: The aim of this study was to investigate the effect of a botulinum toxin type A (BTX-A) injection in the masseter muscle using electromyography (EMG) in an animal model.
Methods: Ten male adult (>3 months of age) New Zealand white rabbits were used. Muscle activity was continuously recorded from 8 hours before to 8 hours after BTX-A injection. The rabbits received unilateral BTX-A injections of either 5 units (group 1, n?=?5) or 20 units (group 2, n?=?5).
Results: The masseter muscle activity of the rabbits was significantly reduced immediately after BTX-A injection (P?0.05 for both groups). When the results from group 1 were compared with those from group 2, only the peak voltage was significantly decreased in group 2 (P?=?0.013).
Conclusion: Masseter muscle activity measured by EMG was immediately decreased after a BTX-A injection.
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Botulinum toxin type A; Electromyography; Masseter muscle; Peak voltage
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